Undervisningsform: theory.
One double lecture per day for two weeks including group work.
10 consecutive days and 2-3 hours per day plus extensive group- and homework. Starting time 9:15. |
Evalueringsform: Mundtlig fremlæggelse og bedømmelse af rapport(er)
Group report and oral defence |
| Karakter: bestået/ikke bestået |
| Obligatoriske forudsætninger: Masters degree in Chemical Engeneering or equivalent |
| Kursusmål: The aim is to give an introduction to the field of combinatorial and solid-phase chemistry. |
| Kursusindhold: Introduction to and history of combinatorial science, comprising both solution and solid-phase synthesis. The mathematics of combinatorics. Molecular diversity (structural and functional properties, the combinatorial display and size). Planning of a library synthesis.Resins and handles for solid-phase peptide, oligonucleotide, oligosaccharide, and organic synthesis. Methods for attachment and cleavage; stability and compatibility during synthesis. Organic syntheses on solid-phase. Analytical techniques. Assays and screening. Phage display libraries Application of combinatorial chemistry in the pharma industry |
| Bemærkninger: Deadline 17-04-2002 |
| Kontaktperson: John Nielsen, building 201, (+45) 4525 2131, jni@kemi.dtu.dk |
