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Archive 1999/2000

10460 Advanced Biophysics: Protein Structure and Dynamics Danish title: Avanceret biofysik: Protein struktur og dynamik Language: English Credit points: 5 Type:  Language: English Prerequisite: TF- eller K-fagpakke, 10201 eller 21270 Recommended semester: 7th - 9th semester Scope and form: Lectures Examination: Written exam (13-scale) Participant limitation: min. 10 Remarks: Advanced Biophysics Contact person:  Henrik Bohr, Building 309, Tel. +45 4525 3141, email hbohr@fysik.dtu.dk, http://info.fysik.dtu.dk/qup-1/henrik.htm Department: Department of Physics Aim: The course is supposed to be a basis for research and development through advanced application of physics and chemistry in bio-technology. Focussing on the protein aspects of modern molecular biology but with novel, material science ideas, the course should bring the students to the frontiers of modern biophysics Contents: Protein modelling and structure prediction. Experimental methods for protein structure determination. Importance of proteins, protein structure, material science properties of peptidechains, sigma/pi orbitals, secondary structures, hydrogen bonding, protein classification, protein folding, side-chain packing, protein dynamics (intrinsic/ektrinsic), electron density calculations, protein conformation, DNA/RNA protein function, reaction kinetics, enzymatic networks